Driven progressive evolution of genome sequence complexity in Cyanobacteria
Metadatos
Mostrar el registro completo del ítemAutor
Moya, Andrés; Hervas Oliver, José Luis; Gómez Martín, Cristina; Lebrón Aguilar, Ricardo; Román Roldán, RamónEditorial
NATURE RESEARCH
Fecha
2020Referencia bibliográfica
Moya, A., Oliver, J.L., Verdú, M. et al. Driven progressive evolution of genome sequence complexity in Cyanobacteria. Sci Rep 10, 19073 (2020). https://doi.org/10.1038/s41598-020-76014-4
Patrocinador
Generalitat Valenciana Prometeo/2018/A/133; European Union (EU); Fulbright fellowship (Spanish Minister of Science, Innovation and Universities); SAF2015-65878-R; AGL2017-88702-C2-2-R; PGC2018-099344-B-I00Resumen
Progressive evolution, or the tendency towards increasing complexity, is a controversial issue
in biology, which resolution entails a proper measurement of complexity. Genomes are the best
entities to address this challenge, as they encode the historical information of a species’ biotic
and environmental interactions. As a case study, we have measured genome sequence complexity
in the ancient phylum Cyanobacteria. To arrive at an appropriate measure of genome sequence
complexity, we have chosen metrics that do not decipher biological functionality but that show
strong phylogenetic signal. Using a ridge regression of those metrics against root-to-tip distance,
we detected positive trends towards higher complexity in three of them. Lastly, we applied three
standard tests to detect if progressive evolution is passive or driven—the minimum, ancestor–
descendant, and sub-clade tests. These results provide evidence for driven progressive evolution at
the genome-level in the phylum Cyanobacteria.