Physical fitness and physical activity association with cognitive function and quality of life: baseline cross-sectional analysis of the PREDIMED-Plus trial
Metadatos
Afficher la notice complèteEditorial
Springer Nature
Materia
Epidemiology Quality of life
Date
2020-02-26Referencia bibliográfica
Daimiel, L., Martínez-González, M.A., Corella, D. et al. Physical fitness and physical activity association with cognitive function and quality of life: baseline cross-sectional analysis of the PREDIMED-Plus trial. Sci Rep 10, 3472 (2020). [https://doi.org/10.1038/s41598-020-59458-6]
Patrocinador
Spanish government, ISCIII, through the Fondo de Investigacion para la Salud (FIS) - European Regional Development Fund PI13/00673 PI13/00492 PI13/00272 PI13/01123 PI13/00462 PI13/00233 PI13/02184 PI13/00728 PI13/01090 PI13/01056 PI14/01722 PI14/0147 PI14/00636 PI14/00972 PI14/00618 PI14/00696 PI14/01206 PI14/01919 PI14/00853 PI14/01374 PI16/00473 PI16/00662 PI16/01873; Especial Action Project entitled: Implementacion y evaluacion de una intervencion intensiva sobre la actividad fisica Cohorte PREDIMED-Plus; Recercaixa grant 2013ACUP00194; Junta de Andalucía PI0458/2013 PS0358/2016 PI0137/2018; Generalitat Valenciana PROMETEO/2017/017; SEMERGEN grant; European Union (EU) CB06/03; Spanish Ministry of Education, Culture and Sports FPU 17/01925; European Research Council (ERC) 340918; PI17/00215; PI17/01441; PI17/00508; PI17/01732; PI17/00926; PI19/00957; PI19/00386; PI19/00309; PI19/01032; PI19/00576; PI19/00017; PI19/01226; PI19/00781; PI19/01560; PI19/01332; PI16/01094; PI16/00501; PI16/00533; PI16/00381; PI16/00366; PI16/01522; PI16/01120; PI17/00764; PI17/01183; PI17/00855; PI17/01347; PI17/00525; PI17/01827; PI17/00532Résumé
Physical activity (PA) has been hypothesized to be effective to maintaining cognitive function and delay cognitive decline in the elderly, but physical fitness (PF) could be a better predictor of cognitive function. We aimed to study the association between PA and PF with cognitive function and quality of life using cross-sectional data from 6874 participants of the PREDIMED-Plus trial (64.9 ± 4.9 years, 48.5% female). PF and PA were measured with a Chair Stand Test, the REGICOR and Rapid Assessment Physical Activity questionnaires. Cognitive function was measured with Mini-mental State Examination, Control Oral Word Association Test, Trail Making Test and Digit Span tests; whereas health-related quality of life was assessed with the SF36-HRQL test. Cognitive and quality of life scores were compared among PF quartiles and PA levels (low, moderate and high) with ANCOVA and with Chair Stand repetitions and energy expenditure from total PA with multivariable linear regression adjusted for confounding factors. PF associated with higher scores in phonemic and semantic verbal fluency tests and with lower TMT A time. However, PA was not associated with the neurocognitive parameters evaluated. Both PF and PA levels were strongly associated with a better quality of life. We concluded that PF, but not PA, is associated with a better cognitive function. This trial was retrospectively registered at the International Standard Randomized