Dietary Polyphenol Intake is Associated with HDL-Cholesterol and A Better Profile of Other Components of the Metabolic Syndrome: A PREDIMED-Plus Sub-Study
Metadatos
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MDPI
Materia
Polyphenols Metabolic syndrome Mediterranean diet Glignans Stilbenes HDL-cholesterol
Date
2020-03Referencia bibliográfica
Castro-Barquero, S., Tresserra-Rimbau, A., Vitelli-Storelli, F., Doménech, M., Salas-Salvadó, J., Martín-Sánchez, V., ... & Romaguera, D. (2020). Dietary Polyphenol Intake is Associated with HDL-Cholesterol and A Better Profile of other Components of the Metabolic Syndrome: A PREDIMED-Plus Sub-Study. Nutrients, 12(3), 689. [doi:10.3390/nu12030689]
Patrocinador
The PREDIMED-Plus trial was supported by official Spanish institutions for funding scientific biomedical research, CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn) and Instituto de Salud Carlos III (ISCIII), through the Fondo de Investigación para la Salud (FIS), which is co-funded by the European Regional Development Fund (four coordinated FIS projects led by J.S.-S. and J.Vi., including the following projects: PI13/00673, PI13/00492, PI13/00272, PI13/01123, PI13/00462, PI13/00233, PI13/02184, PI13/00728, PI13/01090, PI13/01056, PI14/01722, PI14/00636, PI14/00618, PI14/00696, PI14/01206, PI14/01919, PI14/00853, PI14/01374, PI14/00972, PI14/00728, PI14/01471, PI16/00473, PI16/00662, PI16/01873, PI16/01094, PI16/00501, PI16/00533, PI16/00381, PI16/00366, PI16/01522, PI16/01120, PI17/00764, PI17/01183, PI17/00855, PI17/01347, PI17/00525, PI17/01827, PI17/00532, PI17/00215, PI17/01441, PI17/00508, PI17/01732, and PI17/00926), the Special Action Project entitled: Implementación y evaluación de una intervención intensiva sobre la actividad física Cohorte PREDIMED-Plus grant to J.S.-S., the Recercaixa grant to J.S.-S. (2013ACUP00194), a grant from the Fundació la Marató de TV3 (PI044003), grants from the Consejería de Salud de la Junta de Andalucía (PI0458/2013, PS0358/2016, and PI0137/2018),grants from the Generalitat Valenciana (PROMETEO/2017/017, APOSTD/2019/136), a SEMERGEN grant, a CICYT grant provided by the Ministerio de Ciencia, Innovación y Universidades (AGL2016-75329-R) and funds from the European Regional Development Fund (CB06/03). The Spanish Ministry of Science Innovation and Universities for the Formación de Profesorado Universitario (FPU17/00785) contract. Food companies Hojiblanca (Lucena, Spain) and Patrimonio Comunal Olivarero (Madrid, Spain) donated extra virgin olive oil, and the Almond Board of California (Modesto, CA), American Pistachio Growers (Fresno, CA), and Paramount Farms (Wonderful Company, LLC, Los Angeles, CA) donated nuts. This call is co-financed at 50% with charge to the Operational Program FSE 2014-2020 of the Balearic Islands.Résumé
Dietary polyphenol intake is associated with improvement of metabolic disturbances.
The aims of the present study are to describe dietary polyphenol intake in a population with metabolic
syndrome (MetS) and to examine the association between polyphenol intake and the components
of MetS. This cross-sectional analysis involved 6633 men and women included in the PREDIMED
(PREvención con DIeta MEDiterranea-Plus) study. The polyphenol content of foods was estimated
from the Phenol-Explorer 3.6 database. The mean of total polyphenol intake was 846 ± 318 mg/day.
Except for stilbenes, women had higher polyphenol intake than men. Total polyphenol intake was
higher in older participants (>70 years of age) compared to their younger counterparts. Participants
with body mass index (BMI) >35 kg/m2
reported lower total polyphenol, flavonoid, and stilbene
intake than those with lower BMI. Total polyphenol intake was not associated with a better profile
concerning MetS components, except for high-density lipoprotein cholesterol (HDL-c), although
stilbenes, lignans, and other polyphenols showed an inverse association with blood pressure, fasting
plasma glucose, and triglycerides. A direct association with HDL-c was found for all subclasses
except lignans and phenolic acids. To conclude, in participants with MetS, higher intake of several
polyphenol subclasses was associated with a better profile of MetS components, especially HDL-c.