Speed of Retinal Vascularization in Retinopathy of Prematurity: Risk and Protective Factors
Metadatos
Afficher la notice complèteAuteur
Solans Pérez de Larraya, Ana María; Ortega-Molina, JM; Uberos Fernández, José; González Ramírez, Amanda Rocío; García Serrano, José LuisEditorial
Hindawi
Date
2019Referencia bibliográfica
Solans Pérez de Larraya, A. M., Ortega Molina, J. M., Uberos Fernández, J., González Ramírez, A. R., & García Serrano, J. L. (2019). Speed of Retinal Vascularization in Retinopathy of Prematurity: Risk and Protective Factors. BioMed research international, 2019.
Résumé
Objective.The objective was to study the risk and protective factors involved in retinal vascular development of preterminfantswith
retinopathy of prematurity. Methods. Between 2000 and 2017, 185 preterm infants were included in the protocol for retinopathy of
prematurity. Risk factors associated with speed of retinal vascularization <0.5 disc diameter/week were studied in each of them.
Results.The statistically significant variables related to retinal vascular development <0.5 DD/w were intubation days, degree 3 of
bronchopulmonary dysplasia, weight gain at 4-6 weeks, avascular temporal area, gestational age, number of transfusions, sepsis,
number of risk factors, apnea at birth, presence of ductus arteriosus, and days of continuous positive airway pressure therapy. After
the multivariate logistic regression analysis, only three variables were found to be significant: intubation days (p=0.005), degree
3 of bronchopulmonary dysplasia (p=0.022), and weight gain at 4–6 weeks (p=0.031). Conclusion. In retinopathy of prematurity,
degree 3 of bronchopulmonary dysplasia and intubation days cause delayed retinal vascular development,whereas greater postnatal
weight gain favors an appropriate rate of retinal vascularization.