A bioinspired hybrid silica–protein material with antimicrobial activity by iron uptake

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URI: http://hdl.handle.net/10481/47230
ISSN: 1756-5901
ISSN: 1756-591x
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Author
Carmona Rodríguez-Acosta, Fernando; Mendoza, Daniela; Megía Fernández, Alicia; Santoyo González, Francisco; Domínguez Vera, José Manuel
Editorial
Royal Society of Chemistry
Materia
Iron
 
Antimicrobial
 
Ferritin
 
Lactoferrin
 
Date
2013
Referencia bibliográfica
Carmona Rodríguez-Acosta, F.; et al. A bioinspired hybrid silica–protein material with antimicrobial activity by iron uptake. Metallomics, 5: 193-196 (2013). [http://hdl.handle.net/10481/47230]
Sponsorship
This work was supported by MINECO and FEDER (project CTQ2009-09344), Junta de Andalucía (project P07-FQM-02899) and BIOSEARCH SA (contract PostBIO).
Abstract
A silica–protein hybrid material has been prepared by simultaneous covalent deposition of apoferritin and lactoferrin on functionalized silica. This material exhibits strong antibacterial activity against E. coli due to its high iron-uptake capacity.
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