@misc{10481/73811,
year = {2022},
month = {2},
url = {http://hdl.handle.net/10481/73811},
abstract = {Irrigation plays an essential role in root canal treatment. The purpose of this narrative
review was to critically appraise the experimental methods and models used to
study irrigants and irrigation systems and to provide directions for future research.
Studies on the antimicrobial effect of irrigants should use mature multispecies
biofilms grown on dentine or inside root canals and should combine at least two
complementary evaluation methods. Dissolution of pulp tissue remnants should
be examined in the presence of dentine and, preferably, inside human root canals.
Micro-computed
tomography is currently the method of choice for the assessment
of accumulated dentine debris and their removal. A combination of experiments in
transparent root canals and numerical modeling is needed to address irrigant penetration.
Finally, models to evaluate irrigant extrusion through the apical foramen
should simulate the periapical tissues and provide quantitative data on the amount
of extruded irrigant. Mimicking the in vivo conditions as close as possible and standardization
of the specimens and experimental protocols are universal requirements
irrespective of the surrogate endpoint studied. Obsolete and unrealistic models must
be abandoned in favour of more appropriate and valid ones that have more direct
application and translation to clinical Endodontics.},
publisher = {John Wiley & Sons},
keywords = {Biofilm},
keywords = {Debris},
keywords = {Extrusion},
keywords = {Irrigation},
keywords = {Penetration},
keywords = {Pulp tissue},
keywords = {Smear layer},
title = {A critical analysis of research methods and experimental models to study irrigants and irrigation systems},
doi = {10.1111/iej.13710},
author = {Boutsioukis, Christos and Arias Moliz, María Teresa},
}