@misc{10481/69459, year = {2021}, month = {6}, url = {http://hdl.handle.net/10481/69459}, abstract = {Sleep duration is a novel and potentially modifiable risk factor for cancer. We evaluated the association of self-reported sleep duration and daytime napping with odds of colorectal and gastric cancer. We included 2008 incident colorectal cancer cases, 542 gastric cancer cases and 3622 frequency-matched population controls, recruited in the MCC-Spain case–control study (2008–2013). Sleep information, socio-demographic and lifestyle characteristics were obtained through personal interviews. Multivariable adjusted logistic regression models were used to estimate odds ratios (OR) with 95% confidence intervals (CI) for cancer, across categories of sleep duration (≤ 5, 6, 7, 8, ≥ 9 hours/day), daytime napping frequency (naps/week) and duration (minutes/nap). Compared to 7 hours of sleep, long sleep was associated with increased odds of colorectal ( OR≥9 hours: 1.59; 95%CI 1.30–1.94) and gastric cancer ( OR≥9 hours: 1.95; 1.37–2.76); short sleep was associated with increased odds of gastric cancer ( OR≤5 hours: 1.32; 0.93–1.88). Frequent and long daytime naps increased the odds of colorectal ( OR6–7 naps/week, ≥30 min: 1.32; 1.14–1.54) and gastric cancer ( OR6–7 naps/week, ≥30 min: 1.56; 1.21–2.02). Effects of short sleep and frequent long naps were stronger among participants with night shift-work history. Sleep and circadian disruption may jointly play a role in the etiology of colorectal and gastric cancer.}, organization = {Catalan Government DURSI 2009SGR1489,RYC-2017-01892}, organization = {Catalan Institute of Oncology}, organization = {Centro de Investigacion Biomedica en Red: Epidemiologia y Salud Publica}, organization = {Consejería de Salud of the Junta de Andalucía 2009-S0143}, organization = {FEDER funds/European Regional Develpment Fund}, organization = {ICGC International Cancer Genome Consortium CLL}, organization = {ICOBIOBANC}, organization = {Red Temática de Investigación del Cáncer RD12/0036/0036}, organization = {Spanish Association Against Cancer}, organization = {Xarxa de Bancs de Tumors de Cata-lunya}, organization = {Albert Einstein Cancer Center AECC}, organization = {Ministerio de Ciencia, Innovación y Universidades MCIU}, organization = {Eno Scientific Foundation}, organization = {European Commission FOOD-CT-2006-036224-HIWATE EC}, organization = {Generalitat de Catalunya 2017SGR723}, organization = {Agència de Gestió d'Ajuts Universitaris i de Recerca 2017SGR1085 AGAUR}, organization = {Ministerio de Economía y Competitividad MINECO}, organization = {Instituto de Salud Carlos III PI08/0533,PI08/1359,PI08/1770,PI11/00226,PI11/01403,PI11/01810,PI11/02213,PI12/00150,PI12/00265,PI12/00488,PI12/00715,PI12/01270 ISCIII}, organization = {Ministerio de Ciencia e Innovación CEX2018-000806-S MICINN}, organization = {European Social Fund ESF}, organization = {European Regional Development Fund PI17/01280 ERDF}, organization = {Conselleria de Sanitat Universal i Salut Pública 2010ACUP 00310,AP_061/10}, organization = {Junta de Castilla y León LE22A10-2}, organization = {Fundación Marqués de Valdecilla API 10/09 FMV}, publisher = {Springer Nature}, title = {Sleep duration and napping in relation to colorectal and gastric cancer in the MCC‑Spain study}, doi = {10.1038/s41598-021-91275-3}, author = {Papantoniou, Kyriaki and Jiménez Moleón, José Juan and Olmedo Requena, María Rocío}, }