@misc{10481/66865,
year = {2021},
month = {1},
url = {http://hdl.handle.net/10481/66865},
abstract = {The current study was designed to assess the influence of consumption of ultra-processed
(UPF) on oxidative/antioxidant balance and evoked inflammatory signaling in young patients with
celiac disease (CD). The study included 85 children. The celiac group (n = 53) included children with
CD with a long (>18 months, n = 17) or recent (<18 months, n = 36) adherence to a gluten-free diet
(GFD). The control group (n = 32) included healthy children with a significantly lower consumption
of UPF compared to the CD group, both expressed as kcal/day (p = 0.043) and as percentage of
daily energy intake (p = 0.023). Among children with CD, the group with the lowest consumption
of UPF (below the 50% of daily energy intake) had a greater Mediterranean diet (MD) adherence
and higher moderate physical activity levels. In addition, CD children with the lowest consumption
of UPF had healthier redox (lower soluble superoxide dismutase-1 and 15-F2t-isoprostanes) and
inflammatory profiles (lower macrophage inflammatory protein-1 ) compared to the group with the
highest consumption of UPF (all, p < 0.05) regardless of the time on a GFD. These findings highlight
the importance of a correct monitoring of the GFD. An unbalanced GFD with high consumption
of UPF and an unhealthy pattern with less physical activity and worse adherence to MD results
in a worse inflammatory profile, which could act as a parallel pathway that could have important
consequences on the pathophysiology of the disease.},
organization = {Regional Government of Andalusia, Excellence Research Project 

P12-AGR-2581},
organization = {University of Granada 

PP2017-PIP14},
organization = {Spanish Ministry of Education, Culture and Sports 

FPU17/03715},
publisher = {Mdpi},
keywords = {Celiac disease},
keywords = {Ultra-processed foods},
keywords = {Gluten-free diet},
keywords = {Inflammatory signaling},
keywords = {Oxidative stress},
keywords = {Children},
title = {Influence of Ultra-Processed Foods Consumption on Redox Status and Inflammatory Signaling in Young Celiac Patients},
doi = {10.3390/nu13010156},
author = {Nestares Pleguezuelo, María Teresa and De la Flor Alemany, Marta and Bonavita, Antonela and Aparicio García-Molina, Virginia},
}