@misc{10481/59961,
year = {2019},
url = {http://hdl.handle.net/10481/59961},
abstract = {This study explored the association between inactive time and measures of adiposity, clinical
parameters, obesity, type 2 diabetes and metabolic syndrome components. It further examined the impact of
reallocating inactive time to time in bed, light physical activity (LPA) or moderate-to-vigorous physical activity (MVPA)
on cardio-metabolic risk factors, including measures of adiposity and body composition, biochemical parameters and
blood pressure in older adults. Inactive time was associated with indicators of obesity and the metabolic syndrome. Reallocating 30min per day
of inactive time to 30 min per day of time in bed was associated with lower BMI, waist circumference and glycated
hemoglobin (HbA1c) (all p-values < 0.05). Reallocating 30 min per day of inactive time with 30 min per day of LPA or
MVPA was associated with lower BMI, waist circumference, total fat, visceral adipose tissue, HbA1c, glucose, triglycerides,
and higher body muscle mass and HDL cholesterol (all p-values < 0.05). Inactive time was associated with a poor cardio-metabolic profile. Isotemporal substitution of inactive time
with MVPA and LPA or time in bed could have beneficial impact on cardio-metabolic health.},
organization = {The PREDIMED-Plus trial was supported by the official funding agency for
biomedical research of the Spanish government, ISCIII through the Fondo de
Investigación para la Salud (FIS), which is co-funded by the European
Regional Development Fund (four coordinated FIS projects led by Jordi
Salas-Salvadó and Josep Vidal, including the following projects: PI13/00673,
PI13/00492, PI13/00272, PI13/01123, PI13/00462, PI13/00233, PI13/02184,
PI13/00728, PI13/01090, PI13/01056, PI14/01722, PI14/00636, PI14/00618,
PI14/00696, PI14/01206, PI14/01919, PI14/00853, PI14/01374, PI16/00473,
PI16/00662, PI16/01873, PI16/01094, PI16/00501, PI16/00533, PI16/00381,
PI16/00366, PI16/01522, PI16/01120, PI17/00764, PI17/01183, PI17/00855,
PI17/01347, PI17/00525, PI17/01827, PI17/00532, PI17/00215, PI17/01441,
PI17/00508, PI17/01732, PI17/00926); the Especial Action Project entitled:
Implementación y evaluación de una intervención intensiva sobre la
actividad física Cohorte PREDIMED-PLUS grant to Jordi Salas-Salvadó; the
European Research Council grant (Advanced Research Grant 2013–2019;
340918) to Miguel Ángel Martínez-Gonzalez; the Recercaixa grant to Jordi
Salas-Salvadó (2013ACUP00194); grants from the Consejería de Salud de la
Junta de Andalucía (PI0458/2013; PS0358/2016; PI0137/2018); the
PROMETEO/2017/017 grant from the Generalitat Valenciana; Grant of support
to research groups no. 35/2011 (Balearic Islands Gov. & FEDER funds) to Catalina M. Mascaró and Josep A. Tur; FPU Programme, PhD fellowship
(Spanish Ministry of Science, Innovation & Universities) to Catalina M.
Mascaró; the Astra Zeneca Young Investigators Award in Category of Obesity
and Diabetes 2017 to Dora Romaguera; Juan de la Cierva-formación research
grant (FJCI-2015-24058) of the Spanish Ministry of Economy, Industry and
Competitiveness and European Social Funds to Jadwiga Konieczna; the
‘FOLIUM’ programme within the FUTURMed project from the Fundación
Instituto de Investigación Sanitaria Illes Balears (financed by 2017annual plan
of the sustainable tourism tax and at 50% with charge to the ESF Operational
Program 2014–2020 ofthe Balearic Islands) to Jadwiga Konieczna. JR17/00022
contract to Olga Castaner from ISCIII. CIBERobn (Centros de Investigación
Biomedica en Red: Obesidad y Nutrición), CIBEResp (Centros de Investigación
Biomedica en Red: Epidemiología y Salud Publica) and CIBERdem (Centros
de Investigación Biomedica en Red: Diabetes y Enfermedades).},
publisher = {Springer Nature},
keywords = {Inactive time},
keywords = {Light physical activity},
keywords = {Moderate-to-vigorous physical activity},
keywords = {Time in bed},
keywords = {Cardiometabolic risk},
keywords = {Isotemporal substitution},
title = {Isotemporal substitution of inactive time with physical activity and time in bed: cross-sectional associations with cardiometabolic health in the PREDIMED-Plus study},
doi = {10.1186/s12966-019-0892-4},
author = {Riquelme Gallego, Blanca},
}