@misc{10481/58810,
year = {2020},
month = {2},
url = {http://hdl.handle.net/10481/58810},
abstract = {Creatinine level in urine is a key factor to monitor kidney performance. The use of an alternative microfluidic platform based on cellulose substrates is an interesting option to integrate sample treatment, creatinine re- cognition by ionophore extraction chemistry and quantification by color measurement through consumer electronics imaging devices. The inclusion of ionophore extraction chemistry based on aryl-substituted calix[4] pyrrole synthetic receptor on 8.7 mm long cotton thread permit the sample treatment, optical recognition of creatinine and their quantification by smartphone running app in unfiltered urine samples diluted 1:100 ratio. The device shows a short response time, 30 s, to creatinine over a wide dynamic range (from 1.6× 10 6 to 5 10–2 M) with precision between 2.9–4.3%. The low interference level of representative species in urine is studied and justified by density functional theory (DFT) calculations.},
organization = {“Ministerio de Economía y Competitividad” under Project CTQ2016-78754-C2-1-R},
publisher = {Elsevier},
keywords = {Optical device},
keywords = {µTAD},
keywords = {Creatinine determination},
keywords = {Density functional theory},
keywords = {Calix[4]pyrrole derivative},
keywords = {Smartphone},
title = {Thread based microfluidic platform for urinary creatinine analysis},
doi = {10.1016/j.snb.2019.127407},
author = {Arroyo, Manuel J. and Erenas Rodríguez, Miguel María and Orbe Payá, Ignacio De and Dobado Jiménez, José Antonio and Ballester, Pablo and Blondeau, Pascal and Salinas Castillo, Alfonso and Capitán Vallvey, Luis Fermín and Cantrell, Kevin},
}