@misc{10481/58680,
year = {2019},
month = {11},
url = {http://hdl.handle.net/10481/58680},
abstract = {Bryophytes comprise of the mosses, liverworts, and hornworts. Cryphaea heteromalla,
(Hedw.) D. Mohr, is a non-vascular lower plant belonging to mosses group. To the date, the most
chemically characterized species belong to the liverworts, while only 3.2% and 8.8% of the species
belonging to the mosses and hornworts, respectively, have been investigated. In this work, we present
Folin–Ciocalteu and oxygen radical absorbance capacity (ORAC) data related to crude extracts of C.
heteromalla obtained by three di erent extraction solvents: pure water (WT), methanol:water (80:20
v/v) (MET), and ethanol:water (80:20 v/v) (ETH). The water extract proved to be the best solvent
showing the highest content of biophenols and the highest ORAC value. The C. heteromalla-WT
extract was investigated by HPLC-TOF/MS (High Performance Liquid Chromatography-Time of
Flight/Mass Spectrometry) allowing for the detection of 14 compounds, five of which were phenolic
compounds, derivatives of benzoic, caffeic, and coumaric acids. Moreover, the C. heteromalla WT
extract showed a protective effect against reactive oxygen species (ROS) generation induced by
tert-butyl hydroperoxide (TBH) on the murine NIH-3T3 fibroblast cell line.},
organization = {This work was supported by the European Social Funding (FSE Sicilia 2020 Project ID: 2014.IT.05.SFOP.014/
3/10.4/9.2.10/0014).},
publisher = {MDPI},
keywords = {Bryophytes},
keywords = {Cryphaea heteromalla},
keywords = {Extract HPLC-ESI-TOF-MS analysis},
keywords = {Oxidative stress evaluation},
title = {Water Extract of Cryphaea heteromalla (Hedw.) D. Mohr Bryophyte as a Natural Powerful Source of Biologically Active Compounds},
doi = {10.3390/ijms20225560},
author = {Provenzano, Fiorenza and Lozano Sánchez, Jesús and Borras Linares, María Isabel and Segura Carretero, Antonio},
}