TY  - CHAP 
AU  - Martínez Herrerías, José Cristóbal
AU  - Castillo, Francisco
AU  - Ruiz Sanz, Javier
AU  - Murciano Calles, Javier
AU  - Cámara-Artigas, Ana
AU  - Luque Fernández, Irene
PY  - 2022
UR  - https://hdl.handle.net/10481/99939
AB  - Within the modular protein domains there are five families that recognize proline-rich sequences: SH3, WW, EVH1, GYF and UEV domains. This chapter reviews the main strategies developed for the design of ligands for these families, including peptides,...
LA  - eng
PB  - Elsevier Inc.
KW  - EVH1 domains; GYF domains
KW  - Ligand design
KW  - Polyproline peptides
KW  - Protein-protein interactions
KW  - SH3 domains
KW  - Structure/function relationships in protein domains
KW  - UEV domains; WW domains
TI  - Understanding binding affinity and specificity of modular protein domains: A focus in ligand design for the polyproline-binding families
DO  - https://doi.org/10.1016/BS.APCSB.2021.12.002
ER  -