TY - GEN AU - Medina Carmona, Encarnación AU - Palomino Morales, Rogelio Jesús AU - Fuchs, Julian E. AU - Padín-Gonzalez, Esperanza AU - Mesa Torres, Noel AU - Salido, Eduardo AU - Timson, David J. AU - Pey Rodríguez, Ángel Luis PY - 2016 UR - https://hdl.handle.net/10481/96054 AB - Protein dynamics is essential to understand protein function and stability, even though is rarely investigated as the origin of loss-of-function due to genetic variations. Here, we use biochemical, biophysical, cell and computational biology tools... LA - eng PB - Springer Nature TI - Conformational dynamics is key to understanding loss-of-function of NQO1 cancer-associated polymorphisms and its correction by pharmacological ligands DO - 10.1038/srep20331 ER -