TY - GEN AU - Dash, Sweta AU - Hanson, Sabrina AU - King, Ben AU - Nyswaner, Katherine AU - Foss, Kelcie AU - Tesi, Noelle AU - Harvey, Mungo J.B. AU - Navarro Marchal, Saul Abenhamar AU - Woods, Alison AU - Poradosu, Enrique AU - Unciti-Broceta, Asier AU - Carragher, Neil O. AU - Brognard, John PY - 2024 UR - https://hdl.handle.net/10481/94715 AB - NXP900 is a selective and potent SRC family kinase (SFK) inhibitor, currently being dosed in a phase 1 clinical trial, that locks SRC in the "closed" conformation, thereby inhibiting both kinase-dependent catalytic activity and kinase-independent... LA - eng PB - Elsevier KW - ESCC KW - HNSCC KW - Src family kinases TI - The SRC family kinase inhibitor NXP900 demonstrates potent antitumor activity in squamous cell carcinomas DO - 10.1016/j.jbc.2024.107615 ER -