TY  - GEN 
AU  - Risso, Valeria Alejandra
AU  - Martínez Rodríguez, Sergio
AU  - Candel, Adela M.
AU  - Krüger, Dennis M.
AU  - Pantoja-Uceda, David
AU  - Ortega Muñoz, Mariano
AU  - Santoyo González, Francisco
AU  - Gaucher, Eric A.
AU  - Kamerlin, Shina C.L.
AU  - Bruix, Marta
AU  - Gavira, Jose A.
AU  - Sánchez Ruiz, José Manuel
PY  - 2017
UR  - https://hdl.handle.net/10481/86926
AB  - Protein engineering studies often suggest the emergence of completely new enzyme functionalities to be highly improbable. However, enzymes likely catalysed many different reactions already in the last universal common ancestor. Mechanisms for the...
LA  - eng
PB  - Springer Nature
TI  - De novo active sites for resurrected Precambrian enzymes
DO  - 10.1038/ncomms16113
ER  -