TY - JOUR AU - Rodríguez-Vargas, José Manuel AU - Ruiz Magaña, María José AU - Ruiz Ruiz, Carmen AU - Majuelos-Melguizo, Jara AU - Peralta-Leal, Andreína AU - Rodríguez, M.I. AU - Muñoz-Gámez, José Antonio AU - Ruiz de Almodóvar, Mariano AU - Siles, E. AU - López-Rivas, Abelardo AU - Jäättela, M. AU - Oliver, Francisco Javier PY - 2012 UR - https://hdl.handle.net/10481/86546 AB - In response to nutrient stress, cells start an autophagy program that can lead to adaptation or death. The mechanisms underlying the signaling from starvation to the initiation of autophagy are not fully understood. In the current study we show that... LA - eng PB - NATURE-SHANGAI INSTITUTES FOR BIOLOGICAL SCIENCES KW - Starvation KW - Autophagy KW - DNA damage KW - PARP-1 KW - mTOR KW - AMPK TI - ROS-induced DNA damage and PARP-1 are required for optimal induction of starvation-induced autophagy DO - 10.1038/cr.2012.70 ER -