TY - GEN AU - Medina Moreno, Ana AU - El-Hammadi, Mazen M. AU - Arias Mediano, José Luis PY - 2023 UR - https://hdl.handle.net/10481/83905 AB - Tegafur is used to treat various malignant lesions, including advanced gastric and colorectal cancers. However, its efficacy is limited by its low oral bioavailability, short half-life and serious toxicity. To address these drawbacks, a... LA - eng PB - Elsevier KW - Poly(ε-caprolactone) KW - Chitosan KW - Tegafur KW - Nanoparticles KW - Colorectal cancer KW - Drug delivery TI - pH-dependent, extended release and enhanced in vitro efficiency against colon cancer of Tegafur formulated using chitosan-coated poly (ε-caprolactone) nanoparticles DO - 10.1016/j.jddst.2023.104594 ER -