TY  - GEN 
AU  - Espejo Román, José Manuel
AU  - Rubio Ruiz, Belén
AU  - Chayah Ghaddab, Meriem
AU  - Sánchez Martín, Rosario María
AU  - Cruz López, Olga María
AU  - Conejo García, Ana
PY  - 2023
UR  - https://hdl.handle.net/10481/83692
AB  - Hyaluronic acid (HA) plays a crucial role in tumor growth and invasion through its interaction with cluster of differentiation 44 (CD44), a non-kinase transmembrane glycoprotein, among other hyaladherins. CD44 expression is elevated in many solid...
LA  - eng
PB  - Elsevier
KW  - Hyaluronic acid
KW  - Cluster of differentiation 44
KW  - Tetrahydroisoquinoline
KW  - Molecular dynamics simulations
KW  - Antiproliferative effect
KW  - Three-dimensional cancer model evaluation
TI  - N-Aryltetrahydroisoquinoline derivatives as HA-CD44 interaction inhibitors: design, synthesis, computational studies, and antitumor effect
DO  - 10.1016/j.ejmech.2023.115570
ER  -