TY - GEN AU - Medina Carmona, Encarnación AU - Gutiérrez Rus, Luis Ignacio AU - Manssour Triedo, Fadia AU - Gámiz Arco, María Gloria AU - Mota Ávila, Antonio José AU - Reiné Díaz, Pablo AU - Ortega Muñoz, Mariano AU - Andrés León, Eduardo AU - Ibarra Molero, Beatriz AU - Sánchez Ruiz, José Manuel PY - 2023 UR - https://hdl.handle.net/10481/81378 AB - Many metabolites are generated in one step of a biochemical pathway and consumed in a subsequent step. Such metabolic intermediates are often reactive molecules which, if allowed to freely diffuse in the intracellular milieu, could lead to... LA - eng PB - Oxford University Press KW - Auxotrophy rescue KW - Prototrophy restoration KW - Metabolic innovation KW - Labile metabolic intermediates KW - Evolutionary repair experiments KW - Laboratory evolution TI - Cell Survival Enabled by Leakage of a Labile Metabolic Intermediate DO - 10.1093/molbev/msad032 ER -