TY - GEN AU - De Frutos Lucas, Jaisalmer AU - Erickson, Kirk I. PY - 2023 UR - https://hdl.handle.net/10481/80433 AB - Background Wide evidence suggests that physical activity (PA) confers protection against Alzheimer’s disease (AD). On the other hand, the apolipoprotein E gene (APOE) ε4 allele represents the greatest genetic risk factor for developing AD. Extensive... LA - eng PB - BMC KW - APOE ε4 KW - Alzheimer’s disease KW - Physical activity KW - Amyloid pathology KW - Tau pathology KW - Cerebrovascular health KW - Neurotrophic factors KW - Neuroinflammation KW - Glucose metabolism KW - Mitochondrial dysfunction TI - How does apolipoprotein E genotype influence the relationship between physical activity and Alzheimer’s disease risk? A novel integrative model DO - 10.1186/s13195-023-01170-4 ER -