TY - GEN AU - Ruiz Cantero, María del Carmen AU - Cortés-Montero, Elsa AU - Jain, Aakanksha AU - Montilla-García, Ángeles AU - Bravo-Caparrós, Inmaculada AU - Shim, Jaehoon AU - Sánchez-Blázquez, Pilar AU - Woolf, Clifford J. AU - Baeyens, José M. AU - Cobos del Moral, Enrique José PY - 2022 UR - https://hdl.handle.net/10481/78767 AB - Background and Purpose: Peripheral sensitization contributes to pathological pain. While prostaglandin E2 (PGE2) and nerve growth factor (NGF) sensitize peptidergic C-nociceptors (TRPV1+), glial cell line-derived neurotrophic factor (GDNF) sensitizes... LA - eng KW - endomorphin-2 KW - resiniferatoxin KW - Sigma-1 receptors KW - TRPV1 KW - μ-opioid receptors TI - The sigma-1 receptor curtails endogenous opioid analgesia during sensitization of TRPV1 nociceptors DO - 10.1111/bph.16003 ER -