TY - GEN AU - Altea-Manzano, Patricia AU - Sánchez Martín, Rosario María AU - Martín Hernández, Miguel PY - 2022 UR - https://hdl.handle.net/10481/78331 AB - Inhibition of the electron transport chain (ETC) prevents the regeneration of mitochondrial NAD+, resulting in cessation of the oxidative tricarboxylic acid (TCA) cycle and a consequent dependence upon reductive carboxylation for aspartate synthesis.... LA - eng PB - Elsevier KW - Respiration KW - Metabolism KW - Redox KW - Redox transfer KW - Mitochondrion KW - Anaplerosis KW - Cancer KW - Cancer metabolism TI - Reversal of mitochondrial malate dehydrogenase 2 enables anaplerosis via redox rescue in respiration-deficient cells DO - 10.1016/j.molcel.2022.10.005 ER -