TY - JOUR AU - Ruz, Clara AU - Alcantud, José Luis AU - Vives Montero, Francisco AU - Arrebola Vargas, Francisco Jesús AU - Durán Ogalla, Raquel PY - 2022 UR - http://hdl.handle.net/10481/76497 AB - Mutations in LRRK2 and GBA1 are key contributors to genetic risk of developing Parkinson’s disease (PD). To investigate how LRRK2 kinase activity interacts with GBA and contributes to lysosomal dysfunctions associated with the pathology of PD. The... LA - eng PB - MDPI KW - LRRK2 KW - Lysosomal dysfunction KW - Glucocerebrosidase KW - Parkinson's disease KW - Autophagy TI - Seventy-Two-Hour LRRK2 Kinase Activity Inhibition Increases Lysosomal GBA Expression inH4, a Human Neuroglioma Cell Line DO - 10.3390/ijms23136935 ER -