TY - JOUR AU - Morell, María AU - Varela, Nieves AU - Castillejo López, Casimiro AU - Coppard, Céline AU - Luque, María José AU - Martín Morales, Natividad AU - Pérez Cózar, Francisco AU - Gómez Hernández, Gonzalo AU - O'Valle Ravassa, Francisco Javier AU - Alarcón Riquelme, Marta Eugenia AU - Marañón Lizana, Concepción PY - 2022 UR - http://hdl.handle.net/10481/75465 AB - Summary Background Type I IFN (IFN-I) is a family of cytokines involved in the pathogenesis of autoimmune and autoinflammatory diseases such as psoriasis. SIDT1 is an ER-resident protein expressed in the lymphoid lineage, and involved in anti-viral... LA - eng PB - Elsevier KW - SIDT1 KW - pDC KW - IFN-I KW - Proinflammatory cytokines KW - TLR7 KW - TLR9 KW - IRF7 KW - Psoriasis TI - SIDT1 plays a key role in type I IFN responses to nucleic acids in plasmacytoid dendritic cells and mediates the pathogenesis of an imiquimod-induced psoriasis model DO - 10.1016/j.ebiom.2021.103808 ER -