TY - GEN AU - Gavira Gallardo, José Antonio AU - Torres De Pinedo, Jesús Manuel AU - Sánchez Medina, María Pilar AU - Ortega Sánchez, Esperanza AU - Martínez Rodríguez, Sergio PY - 2022 UR - http://hdl.handle.net/10481/74975 AB - Choline-O-sulfatase (COSe; EC 3.1.6.6) is a member of the alkaline phosphatase (AP) superfamily, and its natural function is to hydrolyze choline-O-sulfate into choline and sulfate. Despite its natural function, the major interest in this enzyme... LA - eng PB - International Union of Crystallography KW - Choline KW - Sulfatases KW - Conformational gating KW - Alkaline phosphatases KW - Promiscuity TI - Structural insights into choline-O-sulfatase reveal the molecular determinants for ligand binding DO - 10.1107/S2059798322003709 ER -