TY - GEN AU - Pacheco García, Juan Luis AU - Mesa Torres, Noel AU - Pey Rodríguez, Ángel Luis PY - 2021 UR - http://hdl.handle.net/10481/72134 AB - The phosphomimetic mutation S82D in the cancer-associated, FADdependent human NADP(H):quinone oxidoreductase 1 (hNQO1) causes a decrease in flavin-adenine dinucleotide-binding affinity and intracellular stability. We test in this work whether the... LA - eng PB - John Wiley & Sons KW - Epistasis KW - Flavoprotein KW - Molecular evolution KW - Protein phosphorylation TI - A single evolutionarily divergent mutation determines the different FAD-binding affinities of human and rat NQO1 due to site-specific phosphorylation DO - 10.1002/1873-3468.14238 ER -