TY - JOUR AU - Pacheco García, Juan Luis AU - Palomino Morales, Rogelio Jesús AU - Mesa-Torres, Noel AU - Pey Rodríguez, Ángel Luis PY - 2021 UR - http://hdl.handle.net/10481/71178 AB - The multifunctional nature of human flavoproteins is critically linked to their ability to populate multiple conformational states. Ligand binding, post-translational modifications and disease-associated mutations can reshape this functional... LA - eng PB - Elsevier KW - Flavoprotein KW - Multifunctional proteins KW - Ligand binding KW - Disease-causing mutation KW - Post-translational modification KW - NQO1 TI - Structural basis of the pleiotropic and specific phenotypic consequences of missense mutations in the multifunctional NAD(P)H:quinone oxidoreductase 1 and their pharmacological rescue DO - 10.1016/j.redox.2021.102112 ER -