TY - JOUR AU - Garrido, MarĂ­a Antonia AU - Ruiz-Cabello Osuna, Francisco AU - Garrido Torres-Puchol, Federico AU - Aptsiauri, Natalia PY - 2021 UR - http://hdl.handle.net/10481/70833 AB - Total or partial loss of HLA class I antigens reduce the recognition of specific tumor peptides by cytotoxic T lymphocytes favoring cancer immune escape during natural tumor evolution. These alterations can be caused by genomic defects, such as loss... LA - eng PB - MDPI KW - Cancer immune escape KW - HLA class I KW - Copy-neutral loss of heterozygosity (CN-LOH) KW - Antigen presentation KW - Beta2-microglobulin KW - Cytotoxic T-cells KW - Cancer immunotherapy TI - Copy Neutral LOH Affecting the Entire Chromosome 6 Is a Frequent Mechanism of HLA Class I Alterations in Cancer DO - 10.3390/cancers13205046 ER -