TY  - JOUR 
AU  - Cano Muñoz, Mario
AU  - Cesaro, Samuele
AU  - Morel, Bertrand
AU  - Conejero Lara, Francisco
PY  - 2021
UR  - http://hdl.handle.net/10481/67927
AB  - A promising strategy to neutralize HIV‐1 is to target the gp41 spike subunit to block
membrane fusion with the cell. We previously designed a series of single‐chain proteins (named
covNHR) that mimic the trimeric coiled‐coil structure of the gp41...
LA  - eng
PB  - MDPI
KW  - HIV
KW  - AIDS
KW  - Envelope glycoprotein
KW  - Stability
KW  - Fusion inhibitors
KW  - Calorimetry
KW  - Peptides
KW  - Binding
TI  - Extremely Thermostabilizing Core Mutations in Coiled‐Coil Mimetic Proteins of HIV‐1 gp41 Produce Diverse Effects on Target Binding but Do Not Affect Their Inhibitory Activity
DO  - 10.3390/biom 11040566
ER  -