TY  - GEN 
AU  - Anoz Carbonell, Ernesto
AU  - Timson, David J.
AU  - Pey Rodríguez, Ángel Luis
AU  - Medina, Milagros
PY  - 2020
UR  - http://hdl.handle.net/10481/64954
AB  - Human NQO1 [NAD(H):quinone oxidoreductase 1] is a multi-functional and stress-inducible
dimeric protein involved in the antioxidant defense, the activation of cancer prodrugs and the stabilization
of oncosuppressors. Despite its roles in human...
LA  - eng
PB  - Mdpi
KW  - Antioxidant enzymes
KW  - Antioxidant response
KW  - Cancer
KW  - Oxidoreductases
KW  - Enzyme kinetic analysis
KW  - Functional cooperativity
KW  - Hydride transfer
KW  - Kinetic isotope effects
KW  - Quantum tunneling
KW  - Conformational dynamics
TI  - The Catalytic Cycle of the Antioxidant and Cancer-Associated Human NQO1 Enzyme: Hydride Transfer, Conformational Dynamics and Functional Cooperativity
DO  - 10.3390/antiox9090772
ER  -