TY  - GEN 
AU  - López Escámez, José Antonio
AU  - Amanat, Sana
AU  - Requena, Teresa
PY  - 2020
UR  - http://hdl.handle.net/10481/64449
AB  - Exome sequencing has been commonly used to characterize rare diseases by selecting
multiplex families or singletons with an extreme phenotype (EP) and searching for rare variants
in coding regions. The EP strategy covers both extreme ends of a...
LA  - eng
PB  - MDPI
KW  - Genetic epidemiology
KW  - Genetic association studies
KW  - Extreme phenotype
KW  - Exome sequencing
KW  - Tinnitus
TI  - A Systematic Review of Extreme Phenotype Strategies to Search for Rare Variants in Genetic Studies of Complex Disorders
DO  - 10.3390/genes11090987
ER  -