TY - GEN AU - Eijkelkamp, N. AU - Torres de Pinedo, Jesús Manuel PY - 2013 UR - http://hdl.handle.net/10481/64046 AB - Aberrant mechanosensation has an important role in different pain states. Here we show that Epac1 (cyclic AMP sensor) potentiation of Piezo2-mediated mechanotransduction contributes to mechanical allodynia. Dorsal root ganglia Epac1 mRNA levels... LA - eng PB - Nature Publishing Group KW - Protein-Kinase-C KW - Mechanosensitive Ion Channels KW - Sensory neurons KW - Intrathecal morphine KW - Inflammatory pain KW - Neurophatic pain KW - Cell adhesion KW - Epac proteins KW - Rat KW - Sensitization TI - A role for Piezo2 in EPAC1-dependent mechanical allodynia DO - 10.1038/ncomms2673 ER -