TY - GEN AU - Rubio-Ruiz, Belén AU - Serrán-Aguilera, Lucía AU - Hurtado-Guerrero, Ramón AU - Conejo García, Ana PY - 2020 UR - http://hdl.handle.net/10481/63769 AB - Up-regulated choline metabolism, characterized by an increase in phosphocholine (PCho), is a hallmark of oncogenesis and tumor progression. Choline kinase (ChoK), the enzyme responsible for PCho synthesis, has consequently become of a promising drug... LA - eng PB - Wiley KW - Choline Kinase α KW - Inhibitor KW - Cancer TI - Recent advances in the design of Choline kinase α inhibitors and the molecular basis of their inhibition DO - 10.1002/med.21746 ER -