TY - JOUR AU - Mesa Torres, Noel AU - Betancor-Fernández, Isabel AU - Oppici, Elisa AU - Cellini, Barbara AU - Salido, Eduardo AU - Pey Rodríguez, Ángel Luis PY - 2018 SN - 2073-4425 UR - http://hdl.handle.net/10481/55397 AB - Neutral and adaptive mutations are key players in the evolutionary dynamics of proteins at molecular, cellular and organismal levels. Conversely, largely destabilizing mutations are rarely tolerated by evolution, although their occurrence in diverse... LA - eng PB - MDPI KW - Protein stability KW - Conformational diseases KW - Disease-mechanisms KW - Compensatory mutations KW - Molecular therapies KW - Genotype-phenotype correlations TI - Evolutionary Divergent Suppressor Mutations in Conformational Diseases ER -