TY  - GEN 
AU  - León Rodríguez, Daniel Arturo
AU  - Acosta-Herrera, Marialbert
AU  - Carmona López, Francisco David
AU  - Dolade, Nuria
AU  - Vargas, Sofia
AU  - Echevarría, Luis Eduardo
AU  - González, Clara Isabel
AU  - Martín, Javier
PY  - 2018
SN  - 1932-6203
UR  - http://hdl.handle.net/10481/49617
AB  - Tyrosine kinase 2 (TYK2) is a member of the Janus kinases family implicated in the signal transduction of type I interferons and several interleukins. It has been described that genetic mutations within TYK2 lead to multiple deleterious effects in the...
LA  - eng
PB  - Public Library of Science
KW  - Chagas disease
KW  - Cardiomyopathies
KW  - Trypanosoma cruzi
KW  - Cytokines
KW  - Genetics of disease
KW  - Immune response
KW  - Variant genotypes
KW  - Parasitic diseases
TI  - Comprehensive analysis of three TYK2 gene variants in the susceptibility to Chagas disease infection and cardiomyopathy
DO  - 10.1371/journal.pone.0190591
ER  -