TY  - JOUR 
AU  - Fuchs, Julian E.
AU  - Muñoz, Inés G.
AU  - Timson, David J.
AU  - Pey Rodríguez, Ángel Luis
PY  - 2016
SN  - 2046-2069
UR  - http://hdl.handle.net/10481/42968
AB  - Theoretical and experimental evidence has shown that protein function, regulation and degradation are intrinsically linked to the dynamic and fluctuating nature of protein ensembles. However, the effect of missense mutations on catalytic performance...
LA  - eng
PB  - Royal Society of Chemistry
KW  - Genetic diseases
KW  - Protein
KW  - Conformational fluctuations
KW  - Catalysis
KW  - Inherited metabolic diseases
TI  - Experimental and computational evidence on conformational fluctuations as a source of catalytic defects in genetic diseases
DO  - 10.1039/C6RA05499D
ER  -