TY  - JOUR 
AU  - Landeira, David
AU  - Bagci, Hakan
AU  - Malinowski, Andrzej R.
AU  - Brown, Karen E.
AU  - Soza-Ried, Jorge
AU  - Feytout, Amelie
AU  - Webster, Zoe
AU  - Ndjetehe, Elodie
AU  - Cantone, Irene
AU  - Asenjo, Helena G.
AU  - Brockdorff, Neil
AU  - Carroll, Thomas
AU  - Merkenschlager, Matthias
AU  - Fisher, Amanda G.
PY  - 2015
SN  - 2211-1247
UR  - http://hdl.handle.net/10481/37290
AB  - Jarid2 is part of the Polycomb Repressor complex 2 (PRC2) responsible for genome-wide H3K27me3 deposition. Unlike other PRC2-deficient embryonic stem cells (ESCs), however, Jarid2-deficient ESCs show a severe differentiation block, altered colony...
LA  - eng
PB  - Elsevier
KW  - Cell self-renewal
KW  - Epiblast stem-cells
KW  - Beta-catenin
KW  - Gene expression
KW  - Polycom repression
KW  - Pluripotency
TI  - Jarid2 Coordinates Nanog Expression and PCP/Wnt Signaling Required for Efficient ESC Differentiation and Early Embryo Development
DO  - 10.1016/j.celrep.2015.06.060
ER  -