TY - JOUR AU - Mesa-Torres, Noel AU - Fabelo-Rosa, Israel AU - Riverol, Debora AU - Yunta, Cristina AU - Albert, Armando AU - Salido, Eduardo AU - Pey Rodríguez, Ángel Luis PY - 2013 SN - 1932-6203 UR - http://hdl.handle.net/10481/30966 AB - Primary hyperoxaluria type I (PH1) is a conformational disease which result in the loss of alanine:glyoxylate aminotransferase (AGT) function. The study of AGT has important implications for protein folding and trafficking because PH1 mutants may... LA - eng PB - Public Library of Science (PLOS) KW - Chaperone proteins KW - Free energy KW - Homeostasis KW - Mitochondria KW - Mutation KW - Protein aggregation KW - Protein folding KW - Protein interactions TI - The Role of Protein Denaturation Energetics and Molecular Chaperones in the Aggregation and Mistargeting of Mutants Causing Primary Hyperoxaluria Type I ER -