TY  - GEN 
AU  - González-Rey, Elena
AU  - Martínez-Romero, Rubén
AU  - O'Valle Ravassa, Francisco Javier
AU  - Aguilar-Quesada, Rocío
AU  - Conde, Carmen
AU  - Delgado Mora, Mario
AU  - Oliver Pozo, Francisco Javier
PY  - 2007
SN  - 1932-6203
UR  - http://hdl.handle.net/10481/30951
AB  - Poly(ADP-ribose) polymerase-1 (PARP-1) synthesizes and transfers ADP ribose polymers to target proteins, and regulates DNA repair and genomic integrity maintenance. PARP-1 also plays a crucial role in the progression of the inflammatory response, and...
LA  - eng
PB  - Public Library of Science (PLOS)
KW  - Arthritis
KW  - Bone and joint mechanics
KW  - Cartilage
KW  - Cytokines
KW  - Inflammation
KW  - Inflammatory diseases
KW  - Macrophages
KW  - Neutrophils
TI  - Therapeutic Effect of a Poly(ADP-Ribose) Polymerase-1 Inhibitor on Experimental Arthritis by Downregulating Inflammation and Th1 Response
ER  -