TY  - GEN 
AU  - Fuente, Ildefonso M. de la
AU  - Cortés, Jesús M.
AU  - Pelta Mochcovsky, David Alejandro
AU  - Veguillas, Juan
PY  - 2013
SN  - 1932-6203
UR  - http://hdl.handle.net/10481/30927
AB  - Background

The experimental observations and numerical studies with dissipative metabolic networks have shown that cellular enzymatic activity self-organizes spontaneously leading to the emergence of a Systemic Metabolic Structure in the cell,...
AB  - Methodology/Principal Findings

In order to research the systemic mechanisms involved in the regulation of the cellular enzymatic activity we have studied different catalytic activities of a dissipative metabolic network under different external...
AB  - Conclusions/Significance

We have found that the systemic enzymatic activities are governed by attractors with capacity to store functional metabolic patterns which can be correctly recovered from specific input stimuli. The network attractors...
LA  - eng
PB  - Public Library of Science (PLOS)
KW  - Allosteric regulation
KW  - Cell metabolism
KW  - Enzyme metabolism
KW  - Enzyme regulation
KW  - Enzymes
KW  - Memory
KW  - Metabolic networks
KW  - Metabolic processes
TI  - Attractor Metabolic Networks
ER  -