TY  - GEN 
AU  - Begará Morales, Juan Carlos
AU  - López Jaramillo, Francisco Javier
AU  - Sánchez Calvo, Beatriz
AU  - Carreras Engaña, Alfonso
AU  - Ortega Muñoz, Mariano
AU  - Santoyo González, Francisco
AU  - Corpas Aguirre, Francisco Javier
AU  - Barroso, Juan B.
PY  - 2013
SN  - 1471-2229
UR  - http://hdl.handle.net/10481/29650
AB  - Background
S-nitrosylaton is implicated in the regulation of numerous signaling pathways with a diversity of regulatory roles. The high lability of the S-NO bond makes the study of proteins regulated by S-nitrosylation/denitrosylation a challenging...
AB  - Results
The combination of vinyl sulfone silica with GSNO yielded an affinity resin that withstood high ionic strength without shrinking or deforming and that it was suitable to isolate potential GSNO transnitrosylation target candidates. Fractions...
AB  - Conclusions
Vinyl sulfone silica is an open immobilization support that can be turned ad hoc and in a straightforward manner into an affinity resin. Its potential in omic sciences was successfully put to test in the context of the analysis of...
LA  - eng
PB  - Biomed Central
KW  - Amino acids
KW  - Cell cycle
KW  - Cytokines
KW  - Plant proteins
KW  - Helianthus
KW  - Peas
KW  - Sulfones
KW  - S-Nitrosoglutathione
KW  - Silicon dioxide
TI  - Vinyl sulfone silica: application of an open preactivated support to the study of transnitrosylation of plant proteins by S-nitrosoglutathione
ER  -