TY - GEN AU - Harari, Oscar AU - Val Muñoz, María Coral Del AU - Romero-Zaliz, Rocío AU - Shin, Dongwoo AU - Huang, Henry AU - Groisman, Eduardo A. AU - Zwir Nawrocki, Jorge Sergio Igor PY - 2009 SN - 1471-2105 UR - http://hdl.handle.net/10481/28447 AB - Background: A large amount of computational and experimental work has been devoted to uncovering network motifs in gene regulatory networks. The leading hypothesis is that evolutionary processes independently selected recurrent architectural... AB - Results: We have developed a model-based approach to analyze proteobacterial genomes for promoter features that is specifically designed to account for the variability in sequence, location and topology intrinsic to differential gene expression. We... AB - Conclusion: Global transcriptional regulators control multiple promoters by a variety of network motifs. This is clearly the case for the regulatory protein PhoP. In this work, we studied this regulatory protein and demonstrated that understanding... LA - eng PB - Biomed Central KW - Computational biology KW - DNA-Directed RNA Polymerases KW - Escherichia-coli KW - Regulatory networks KW - Salmonella typhi KW - Transcription factors TI - Identifying promoter features of co-regulated genes with similar network motifs DO - 10.1186/1471-2105-10-S4-S1 ER -