TY - GEN AU - Anguita-Ruiz, Augusto AU - Torres-Martos, Álvaro AU - Bustos-Aibar, Mireia AU - Setó-Llorens, Adriá AU - Ruiz-Ojeda, Francisco Javier AU - Moreno, Luis A. AU - Gil, Ángel AU - Gil-Campos, Mercedes AU - Bueno, Gloria AU - Leis, Rosaura AU - Alcalá-Fdez, Jesús AU - Aguilera, Concepción M. PY - 2026 UR - https://hdl.handle.net/10481/112582 AB - Background: Childhood obesity is a major global public-health challenge. Insulin resistance (IR) is a critical driver of later cardiometabolic alterations. A comprehensive understanding of the molecular mechanisms underlying the initial development of... LA - eng PB - BMC KW - DNA methylation KW - Epigenetics KW - Epigenome-wide association study KW - EWAS KW - Insulin Resistance KW - Cardiometabolic risk factors KW - Longitudinal study KW - Pediatric obesity KW - Puberty KW - Whole-genome genotype KW - mQTL TI - Novel epigenetic marks of insulin resistance trajectories in a longitudinal study of childhood obesity DO - https://doi.org/10.1186/s12933-026-03101-7 ER -