TY - GEN AU - Bueno, Clara AU - Ayllon, Veronica AU - Montes Lorenzo, Rosa María AU - Navarro-Montero, Oscar AU - Ramos Mejía, Verónica AU - Real Luna, Pedro José AU - Romero-Moya, Damia AU - Araúzo-Bravo, Marcos J AU - Menendez, Pablo PY - 2013 SN - 0006-4971 UR - https://hdl.handle.net/10481/111588 AB - Mixed-lineage leukemia (MLL)-AF4 fusion arises prenatally in high-risk infant acute pro-B-lymphoblastic leukemia (pro-B-ALL). In human embryonic stem cells (hESCs), MLL-AF4 skewed hematoendothelial specification but was insufficient for... LA - eng PB - American Society of Hematology TI - FLT3 activation cooperates with MLL-AF4 fusion protein to abrogate the hematopoietic specification of human ESCs DO - 10.1182/blood-2012-11-470146 ER -