TY  - GEN 
AU  - Beck, Carole
AU  - Rodríguez-Vargas, José Manuel
AU  - Boehler, Christian
AU  - Robert, Isabelle
AU  - Heyer, Vincent
AU  - Hanini, Najat
AU  - Gauthier, Laurent R.
AU  - Tissier, Agnès
AU  - Schreiber, Valérie
AU  - Elofsson, Mikael
AU  - Reina San Martín, Bernardo
AU  - Dantzer, Francoise
PY  - 2019
UR  - https://hdl.handle.net/10481/110894
AB  - PARP3 has been shown to be a key driver of TGFβ-induced epithelial-to-mesenchymal transition (EMT) and stemness in
breast cancer cells, emerging as an attractive therapeutic target. Nevertheless, the therapeutic value of PARP3 inhibition has
not yet...
LA  - eng
PB  - Springer Nature
KW  - PARP3
KW  - RICTOR/mTORC2
KW  - cancer aggressiveness
KW  - BRCA1
KW  - Synthetic Lethality
TI  - PARP3, a new therapeutic target to alter Rictor/mTORC2 signaling and tumor progression in BRCA1-associated cancers
DO  - 10.1038/s41418-018-0233-1
ER  -