TY  - GEN 
AU  - Schatoff, Emma M
AU  - Goswami, Sunkanya
AU  - Zafra, Maria Paz
AU  - Foronda, Miguel
AU  - Shusterman, Michael
AU  - Leach, Benjamin I
AU  - Katti, Alyna
AU  - Diaz, Bianca J
AU  - Dow, Lukas E
PY  - 2019
SN  - 2159-8290
SN  - 2159-8274
UR  - https://hdl.handle.net/10481/110845
AB  - The majority of colorectal cancers show hyperactivated WNT signaling due to
inactivating mutations in the adenomatous polyposis coli (APC) tumor suppressor.
Genetically restoring APC suppresses WNT and induces rapid and sustained tumor regression,...
LA  - eng
PB  - American Association for Cancer Research
KW  - Colorectal cancer
KW  - APC mutations
KW  - Tankyrase inhibitors
TI  - Distinct Colorectal Cancer–Associated APC Mutations Dictate Response to Tankyrase Inhibition
DO  - 10.1158/2159-8290.CD-19-0289
ER  -