TY - GEN AU - Han, Teng AU - Goswami, Sukanya AU - Hu, Yang AU - Tang, Fanying AU - Zafra, MarĂ­a Paz AU - Murphy, Charles AU - Cao, Zhen AU - Poirier, John T. AU - Khurana, Ekta AU - Elemento, Olivier AU - Hechtman, Jaclyn F. AU - Ganesh, Karuna AU - Yaeger, Rona AU - Dow, Lukas E. PY - 2020 UR - https://hdl.handle.net/10481/110356 AB - The WNT pathway is a fundamental regulator of intestinal homeostasis, and hyperactivation of WNT signaling is the major oncogenic driver in colorectal cancer. To date, there are no described mechanisms that bypass WNT dependence in intestinal tumors.... LA - eng PB - American Association for Cancer Research KW - WNT KW - Colorectal cancer KW - Single cell RNA sequencing TI - Lineage Reversion Drives WNT Independence in Intestinal Cancer DO - 10.1158/2159-8290.CD-19-1536 ER -