TY - GEN AU - Gutiérrez Rojas, Luis AU - García Jiménez, Jesús PY - 2024 UR - https://hdl.handle.net/10481/110352 AB - Background: Treatment-resistant depression (TRD) is defined as the failure of at least two antidepressants in adequate doses and timing during a major depressive episode. Esketamine intranasal (ESK-IN) has been approved by the Food and Drug... LA - eng PB - Sage Journal KW - Intranasal esketamine KW - Treatment-resistant depression KW - Compassionate use TI - Compassionate use of esketamine intranasal in patients with severe major depressive disorder resistant to the treatment DO - 10.1177/02698811241267837 ER -