TY  - GEN 
AU  - Song, Chun-Qing
AU  - Jiang, Tingting
AU  - Richter, Michelle
AU  - Rhym, Luke H.
AU  - Koblan, Luke W.
AU  - Zafra, María Paz
AU  - Schatoff, Emma M.
AU  - Doman, Jordan L.
AU  - Cao, Yueying
AU  - Dow, Lukas E.
AU  - Zhu, Lihua Julie
AU  - Anderson, Daniel G.
AU  - Liu, David R.
AU  - Yin, Hao
AU  - Xue, Wen
PY  - 2020
UR  - https://hdl.handle.net/10481/110174
AB  - Unlike traditional CRISPR-Cas9 homology-directed repair, base editing can correct point mutations without supplying a DNA-repair template. Here, we show in a mouse model of tyrosinemia that hydrodynamic tail-vein injection of plasmid DNA encoding the...
LA  - eng
PB  - Springer Nature
KW  - Base Editing
KW  - Animal models
KW  - CRISPR-CAS9
TI  - Adenine base editing in an adult mouse model of tyrosinemia
DO  - 10.1038/s41551-019-0357-8
ER  -