TY - GEN AU - María Paz, Zafra AU - Marie J, Parsons AU - Alonso-Curbelo, Direna AU - Goswami, Sukanya AU - Schatoff, Emma M. AU - Han, Teng AU - Katti, Alyna AU - Calvo Fernandez, María Teresa AU - Wilkinson, John E. AU - Piskounova, Elena AU - Dow, Lukas E. PY - 2020 UR - https://hdl.handle.net/10481/109763 AB - KRAS is the most frequently mutated oncogene in cancer, yet there is little understanding of how specific KRAS amino acid changes affect tumor initiation, progression, or therapy response. Using high-fidelity CRISPR-based engineering, we created an... LA - eng PB - American Association for Cancer Research KW - KRAS KW - Pancreatic cancer KW - Cancer-associated-mutations KW - Organoids TI - An In Vivo Kras Allelic Series Reveals Distinct Phenotypes of Common Oncogenic Variants DO - 10.1158/2159-8290.CD-20-0442 ER -